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METHODS FOR IDENTIFYING DNA COPY NUMBER CHANGES

2023-01-12 来源:吉趣旅游网
专利内容由知识产权出版社提供

专利名称:METHODS FOR IDENTIFYING DNA COPY

NUMBER CHANGES

发明人:JING HUANG,MICHAEL, H. SHAPERO,KEITH

JONES

申请号:AU2003291481申请日:20031112

公开号:AU2003291481A1公开日:20040603

摘要:Methods of identifying changes in genomic DNA copy number are disclosed.Methods for identifying homozygous deletions and genetic amplifications are disclosed.An array of probes designed to detect presence or absence of plurality of differentsequences is also disclosed. The probes are designed to hybridize to sequences that arepredicted to be present in a reduced complexity sample. The methods may be used todetect copy number changes in cancerous tissue compared to normal tissue. Themethods may be used to diagnose cancer.

申请人:AFFYMETRIX, INC.

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