专利名称:METHODS FOR IDENTIFYING DNA COPY
NUMBER CHANGES
发明人:JING HUANG,MICHAEL, H. SHAPERO,KEITH
JONES
申请号:AU2003291481申请日:20031112
公开号:AU2003291481A1公开日:20040603
摘要:Methods of identifying changes in genomic DNA copy number are disclosed.Methods for identifying homozygous deletions and genetic amplifications are disclosed.An array of probes designed to detect presence or absence of plurality of differentsequences is also disclosed. The probes are designed to hybridize to sequences that arepredicted to be present in a reduced complexity sample. The methods may be used todetect copy number changes in cancerous tissue compared to normal tissue. Themethods may be used to diagnose cancer.
申请人:AFFYMETRIX, INC.
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