专利名称：Therapeutic agent, method of treatment
and method for predicting the severity ofsystemic inflammatory response syndrome(SIRS), diseases caused or accompanied byneutrophil activation
发明人：Kosuke Kuroda,Hiroshi Morimatsu,Hidenori
Wake,Shuji Mori,Masahiro Nishibori,HideoTakahashi,Keyue Liu,KiyoshiTeshigawara,Masakiyo Sakaguchi
申请号：US14995679申请日：20160114公开号：US09696321B2公开日：20170704
摘要：The present invention provides a neutrophil activation regulator comprising ahistidine-rich glycoprotein (HRG) for the treatment of systemic inflammatory responsesyndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseasesaccompanied by neutrophil activation in a subject in need thereof. Further, the presentinvention provides methods for predicting the severity of systemic inflammatory
response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatorydiseases accompanied by neutrophil activation in a subject in need thereof, and methodsfor predicting the survival of a subject with systemic inflammatory response syndrome(SIRS), diseases caused by neutrophil activation and/or inflammatory diseasesaccompanied by neutrophil activation, that comprise determining the blood level of
histidine-rich glycoprotein in the subject.
申请人：National University Corporation Okayama University
地址：Okayama-shi, Okayama JP
国籍：JP
代理机构：Kilyk & Bowersox, P.L.L.C.
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